«Metabolic Effects in Rats of a Diet with a Moderate Level of Medium-Chain Triglyceride«

Ratas. Sin diferencias apreciables en la ingesta energética, las ratas que consumieron ácidos grasos de cadena media (dieta MCT) engordaron menos que las que consumieron ácidos grasos de cadena larga (dieta LCT):

no significant differences were observed in energy intake, daily weight gain and food efficiency ratio (FER, energy intake/body weight gain) between rats fed LF or MCT diets (Table 3).However, by d 21 the weight gain was greater and the FER was 30% (P < 0.05) lower in rats fed the LCT diet than in rats fed the MCT diet

«Combined Intervention of Medium-Chain Triacylglycerol Diet and Exercise Reduces Body Fat Mass and Enhances Energy Expenditure in Rats«

Ratas. Sin diferencias en la ingesta energética:

Food intake did not differ among the four groups

Menor «eficiencia de alimentación» en los grupos cuya grasa era MCT. Menos grasa corporal acumulada (barras negras en comparación con las blancas):

Menor facilidad para engordar si se consumían ácidos grasos de cadena media, tanto si se hacía ejercicio como si no:

«Nutritional Evaluation of Medium-Chain Triglycerides in the Rat«

Ratas. Las dietas sólo se diferenciaban en el tipo de grasa dietética. Menos grasa corporal en el grupo MCT.

In the group receiving the MCT diet, the fat pads were 2.2% of the body weight, as compared with values of 2.5 to 3.1% in the groups receiving the other dietary fats. These data correlate fairly well with the level of fat in the carcass. Animals consuming MCT had the lowest level of carcass fat. Levels of protein and ash in the carcass were similar with all dietary fats.

«Effect of Medium Chain Triglyceride Lipogenesis and Body Fat in the Rat«

Ratas. Tres dietas, dos de las cuales son altas en grasa y se diferencian únicamente en el tipo de grasa. El grupo MCT fue el que menos peso y grasa corporal ganó, aunque no consumió menos calorías que el LCT.

The high fat diets affected body weights in opposite ways according to the length of their triglyceride fatty acids: corn oil (LCT) significantly increased body weight while MCT significantly decreased it, as compared to the low-fat diet. The effect of the high fat diets on adipose tissue weights paralleled their effect on body weight; fat depots were enlarged by the high-LCT diet and were reduced by the high-MCT diet relative to the low-fat diet. MCT feeding versus low-fat diet feeding significantly reduced the weight of epididymal and perirenal adipose tis sues after 4 weeks.

Composición de las dietas, que, como vemos, son idénticas en términos de macronutrientes:

«Metabolic effects induced by long-term feeding of medium-chain triglycerides in the rat«

Ratas. Similar ingesta energética, pero el grupo MCT ganó un 30% menos de peso.

Energy intake was similar in the LCT and MCT groups […]. The weight gain of rats fed MCT diet was 30% less than that of rats fed LF or LCT diets.

Composición de las dietas:

«Lower Weight Gain and Higher Expression and Blood Levels of Adiponectin in Rats Fed Medium-Chain TAG Compared with Long-Chain TAG«

Ratas. Sin diferencia significativa en la ingesta energética, el grupo MCT ganó menos peso:

The body weight gain was significantly lower in the rats fed the MCT diet than in those fed the LCT diet (Table 2). There was no significant difference in food and digestible energy intake between the two diet groups

Las dietas únicamente se diferencian en el tipo de grasa

The experimental diets contained the following ingredients (g/kg): cornstarch, 249.955; casein, 200; test oil, 200; soybean oil, 30; AIN-93G mineral mix (13), 35; AIN-93 vitamin mix (13), 10; cellulose, 269.5; L-cystine, 3; choline bitartrate, 2.5; and TBHQ, 0.045. The soybean oil, MCT, and rapeseed oil were purchased commercially (Nisshin Oillio Group, Tokyo, Japan)

Como vemos en la tabla, la grasa corporal es claramente diferente según la dieta:

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• Triglicéridos de cadena media (en humanos)